What is the meaning of lethally irradiated?
Irradiation or chemotherapy with a lethal dose without reconstitution of the immune system, or reconstitution with production of graft versus host disease.
What is sublethal irradiation?
Sublethal radiation renders an animal transiently immunosuppressed; this is useful for engrafting tumors or hematopoietic stem cells.
Why are mice irradiated?
Experimental reasons for exposing rodents to ionizing radiation are used in the fields of immunology and cancer biology. Irradiation to produce myeloablation preparatory to bone marrow transplantation (BMT) is frequently used.
What irradiated animals?
Irradiation in rodents, by Gamma or Xrays, is often used in the fields of immunology, toxicology and oncology. The most common goal of irradiation in rodents is to damage the immune system, rendering the animals immunosuppressed for engraftment of tumors or hematopoietic stem cells.
What does irradiate mean?
1a : to affect or treat by radiant energy (such as heat) specifically : to treat by irradiation. b : to cast rays of light upon : illuminate. c : to enlighten intellectually or spiritually. 2 : to emit like rays of light : radiate irradiating strength and comfort.
What is light irradiation?
Irradiation is the process by which an object is exposed to radiation. The term irradiation usually excludes the exposure to non-ionizing radiation, such as infrared, visible light, microwaves from cellular phones or electromagnetic waves emitted by radio and TV receivers and power supplies.
What does Myeloablative mean?
Listen to pronunciation. (MY-eh-loh-a-BLAY-shun) A severe form of myelosuppression. Myelosuppression is a condition in which bone marrow activity is decreased, resulting in fewer red blood cells, white blood cells, and platelets.
What is irradiation process?
What is meant by the term irradiated?
Definition of irradiation 1 : exposure to radiation (such as X-rays or alpha particles) 2 : the application of radiation (such as X-rays or gamma rays) for therapeutic purposes or for sterilization (as of food) also : partial or complete sterilization by irradiation.
Why do I irradiate blood?
Irradiating blood components prevents the donor white cells replicating and mounting an immune response against a vulnerable patient causing transfusion-associated-graft-versus-host disease (TA-GvHD).
What is the difference between irradiated and radiated?
As verbs the difference between irradiate and radiate is that irradiate is to throw rays of light upon; to illuminate; to brighten; to adorn with luster while radiate is to extend, send or spread out from a center like radii.
